In a landmark 1966 Southwestern Medical School study, five male college students were confined to bed for three weeks to determine the cardiovascular de-conditioning effects of inactivity on the human body. This photo shows study participants on their beds while the study was under way. The experiment was intended to mimic the effects of long-term manned space flight. Endurance training followed the bed rest. The results were published as a supplement to the journal 'Circulation.'
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